Covid

Although many countries are in lockdown due to COVID-19, patients can travel to Prague for cancer treatment. More info

Proton Therapy for Head and Neck Cancer Patients Reduces Rates of Xerostomia

22.06.2021

Proton therapy can potentially improve the therapeutic ratio over conventional radiation therapy for oropharyngeal cancer by decreasing acute and late toxicity.

An April 2021 study published in the Green Journal by the MD Anderson team retrospectively compared patients with oropharyngeal cancer (OPC) who received conventional radiotherapy (IMRT) and proton therapy (IMPT).

This suggests that proton therapy may offer vital quality of life benefits for patients with tumours occurring in the head and neck region.

With a median follow-up time of 36.2 months, the study reported that moderate to severe xerostomia (dry mouth associated with impaired salivary gland function) was less common in the proton group when compared to the conventional radiotherapy group at 18-24 months (6% vs. 20%; p = 0.025) and at 24-36 months (6% vs. 20%; p = 0.01).

Intensity modulated proton therapy (IMPT), one of the most advanced forms of proton therapy, delivers a precise dose of protons to tumours embedded in the head and neck, including the base of tongue and tonsils. Unlike conventional radiotherapy, which destroys both cancerous and healthy cells, IMPT has the ability to destroy cancer cells while sparing surrounding healthy tissue from damage. Therefore, important quality of life outcomes such as neurocognitive function, vision, swallowing, hearing, taste and speech can be preserved in head and neck cancer patients.

 

Publication:
https://pubmed.ncbi.nlm.nih.gov/33839202/

Contact Us

The Proton Therapy Center in Prague, Czech Republic, is a leading cancer centre dedicated to guiding you through your fight against cancer. Contact us today and our team will get back to you with a detailed response to your needs as soon as possible.

    By sending this form you agree, in accordance with Act 101/2000 Sb. and Regulation 2016/679 (the law on the protection of personal data and GDPR) in the wording of subsequent regulations, to the collection, storage and processing of my personal data according to the Proton Therapy UK Privacy Notice. The PTUK hereby declares that it will collect personal data to the extent necessary to fulfil the fulfilment of the stipulated purpose and process it only in accordance with the purpose for which it was collected.

    Please check your spam email inbox if you do not receive a reply from our team within 2 business days.